A new global review suggests that people exposed to pesticides at work may have a higher risk of Amyotrophic Lateral Sclerosis (ALS), also called Motor Neuron Disease, a rare and progressive disease that damages the nerve cells controlling muscle movement. Pooled data showed about a 60 per cent higher risk among exposed workers, with greater exposure linked to greater risk. The findings may matter in India, where many people work in agriculture. However, the study does not prove cause and effect, as it relied largely on recalled exposure and a limited number of studies. Experts say ALS is likely caused by a mix of genetic susceptibility and environmental factors, and the overall risk remains low. Safer pesticide handling, protective equipment and awareness are important for farm workers. More India-specific research is needed. If you notice persistent muscle weakness, twitching or difficulty with movement, see a neurologist early.