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What Is Ovarian Reserve Discordance? When AMH and Antral Follicle Count Don’t Match

CK Birla Hospital
Nov 10, 2026 Author: CK Birla Hospital Team
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AMH (a blood test) and antral follicle count, or AFC (an ultrasound count of small follicles), are both used to assess ovarian reserve, but their results do not always match. This is called ovarian reserve discordance. A mismatch does not necessarily mean reduced fertility. It can happen because both tests are estimates, ultrasound readings vary, hormonal contraception can affect results, polycystic ovaries can raise both counts, and age and individual biology differ. Doctors read the results along with age, menstrual history and fertility goals. The tests help predict how the ovaries may respond to IVF medicines, but they cannot predict whether IVF will work. A low AMH or AFC also does not make pregnancy impossible. Consider seeing a fertility specialist if your results differ greatly, you are planning IVF or egg freezing, you have had ovarian surgery, or your results seem unexpectedly low or high for your age.

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